The journey to a successful Kidney Transplant: Dr LH Hiranandani Hospital

 A kidney transplant is a surgical procedure to place a robust kidney from a living or deceased donor into a person whose kidneys no longer perform appropriately or to treat kidney failure. 

Kidneys play a vital role in filtering waste and extra compounds from the blood and discarding it from the body through your urine. They also assist in maintaining your body's fluid and electrolyte equilibrium. If the kidneys cease to work, this might steer to waste build-ups and can make you very squeamish.

When kidneys deplete this percolating ability, destructive degrees of fluid and trash accumulate in the body. This can lift up blood pressure and transpire in kidney failure (last-stage renal disease). Last-stage renal disease materializes when the kidneys adrift about 90% of their potential to operate naturally. 

People whose kidneys have ceased to function usually go through a treatment called dialysis. This therapy mechanically filters the junk compounds that accumulate in the bloodstream when the kidneys resist working. In some cases, the person might qualify for a kidney transplant and in this process, one or both the kidneys are supplanted with the donor's kidneys either from a live or deceased person. 

At Hiranandani Hospital Kidney Transplant, healthcare specialists equipped in several medical specialties work jointly as a team to ensure promising outcomes from your kidney transplant.

Having all of this subspecialized mastery in a sole location, directed to you, ensures that you're not just getting one viewpoint — your case is reviewed and discussed among the team, your examination reports are accessible shortly, appointments are planned in accordance with it, and your transplant care team works concurrently to define what's best for you.

Stating the pros and cons of both Dialysis and Kidney transplants, Dr Sujit Chatterjee, CEO of Hiranandani Hospital said- Withstanding dialysis consumes time and is a bit labor-intensive too. Dialysis often requires making periodic visits to a dialysis centre to get the treatment done. At the dialysis centre, your blood is purified by employing a dialysis machine.

If you’re hoping to have dialysis in your home, you’ll need to buy dialysis merchandise and learn how to employ them.

A kidney transplant can exempt you from a long-term dependency on a dialysis machine and the rigid schedule connected to it. This can permit you to subsist a comparatively vigorous life. However, Kidney transplantation isn't suitable for everyone. This includes people having infections and those who are excessively obese.

During a kidney transplant, the surgeon will place an endowed kidney in your body. Despite you’re born with two kidneys, you can lead a decent life with only one operating kidney. After the transplant, you’ll have to take immune-suppressing pills to keep your immune system from ambushing the new, foreign organ. 

During the assessment for a transplant, you’ll have blood tests to examine the blood group (A /B /AB /O) and your Human Leukocyte Antigen (HLA). HLA is a group of Antigens tracked down on the surface of the white blood cells. Antigens are responsible for the body’s immune reaction.

If the patient’s HLA type corresponds to the donor’s HLA type, it has more probability that the kidney won't be rejected. Every person has six antigens, three from each of their biological parent. The higher number of the antigens matched, the better the chance of a triumphant transplant.

Once a probable donor is recognized, the patient will have to undergo another test to ensure that their antibodies won’t sabotage the donor’s organ. This is done by blending a small quantity of your blood with that of the donor’s blood.

The transplant can’t be accomplished if your blood configurations antibodies in response to the donor’s blood.

If no antibody reaction is observed, it's a “negative crossmatch.” This means that the transplant can be progressed.

A kidney transplant is done under anaesthesia, which puts you to sleep during the surgery and is infiltrated into your body through an intravenous (IV) line on the patient’s arm. An incision in the abdomen is made and the kidney is placed inside. The arteries and veins from the kidney to your arteries and veins are connected, causing blood flow through the transplanted kidney. The fresh kidney’s ureter to the urinary bladder is also attached empowering to urinate naturally. 

The original kidneys are left inside the body until they aren't causing problems like infections. 

A kidney transplant is a major surgery and hence involves numerous risks like an allergic reaction to general anaesthesia, an infection, blood clots, bleeding, rejection or failure of the new kidney, a stroke or heart attack etc. 

Although it's unusual that the patient's body will repudiate the donor's kidney, even if it does, dialysis can be resumed as a backup. Dr Sujit Chatterjee says that around ninety per cent of transplant beneficiaries who had a living donor lived for 5 years at least after the transplant, while on the flip side, around 80 per cent of beneficiaries who had deceased donors lived for more than 5 years.

Hiranandani Hospital Kidney has experts, specialists and surgeons there have pioneered many transplants that include both, living and deceased donor transplant procedures. They have extensive experience and skills in complex kidney transplantation types like Positive crossmatch, ABO incompatible and paired-donation kidney transplants.